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  • 产品名称:anti-serpinPeptidaseInhibitor,CladeA(Alpha-1Antiproteinase,Antitrypsin),Member7

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简单介绍:
anti-serpinPeptidaseInhibitor,CladeA(Alpha-1Antiproteinase,Antitrypsin),Member7(SERPINA7)(AA37-65),(N-Term)antibody
详情介绍:
Immunogen This SERPINA7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-65 amino acids from the N-terminal region of human SERPINA7.
Clone RB18486
Purification This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Alternative Name SERPINA7 (SERPINA7 Antibody Abstract)
Background SERPINA7 is the major thyroid hormone transport protein in man . Inherited abnormalities in the level of serum TBG have been classified as partial deficiency, complete deficiency, and excess. Patients are euthyroid.

Synonyms: SERPINA7, TBG, Thyroxine-binding globulin, Serpin A7, T4-binding globulin
NCBI Accession NP_000345
UniProt P05543
Pathways Hormone Transport
Application Notes WB: 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.43 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Supplier Images
Western Blotting (WB) image for anti-serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 7 (SERPINA7) (AA 37-65), (N-Term) antibody (ABIN1881790) SERPINA7 Antibody (N-term) (ABIN1881790) western blot analysis in human blood plasma ...
Background publications Domingues, Font, Sobrinho, Bugalho: "A novel variant in Serpina7 gene in a family with thyroxine-binding globulin deficiency." in: Endocrine, Vol. 36, Issue 1, pp. 83-6, 2009 (PubMed).

Lacka, Nizankowska, Ogrodowicz, Lacki: "A novel mutation (del 1711 G) in the TBG gene as a cause of complete TBG deficiency." in: Thyroid : official journal of the American Thyroid Association, Vol. 17, Issue 11, pp. 1143-6, 2007 (PubMed).

Liu, Qian, Gritsenko, Camp, Monroe, Moore, Smith: "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry." in: Journal of proteome research, Vol. 4, Issue 6, pp. 2070-80, 2005 (PubMed).

Ross, Grafham, Coffey, Scherer, McLay, Muzny, Platzer, Howell, Burrows, Bird, Frankish, Lovell, Howe, Ashurst, Fulton, Sudbrak, Wen, Jones, Hurles, Andrews, Scott, Searle, Ramser, Whittaker, Deadman et al.: "The DNA sequence of the human X chromosome. ..." in: Nature, Vol. 434, Issue 7031, pp. 325-37, 2005 (PubMed).

Anderson, Polanski, Pieper, Gatlin, Tirumalai, Conrads, Veenstra, Adkins, Pounds, Fagan, Lobley: "The human plasma proteome: a nonredundant list developed by combination of four separate sources." in: Molecular & cellular proteomics : MCP, Vol. 3, Issue 4, pp. 311-26, 2004 (PubMed).

Mori, Miura, Takeuchi, Igarashi, Sugiura, Saito, Oiso: "Gene amplification as a cause of inherited thyroxine-binding globulin excess in two Japanese families." in: The Journal of clinical endocrinology and metabolism, Vol. 80, Issue 12, pp. 3758-62, 1996 (PubMed).