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  • 产品名称：anti-UBR7antibody(UbiquitinProteinLigaseE3ComponentN-Recognin7(Putative))(AA100

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简单介绍：
anti-UBR7antibody(UbiquitinProteinLigaseE3ComponentN-Recognin7(Putative))(AA100-128)
详情介绍：
Immunogen This UBR7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 100-128 amino acids from the N-terminal region of human UBR7.
Clone RB40614
Purification This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Alternative Name UBR7 (UBR7 Antibody Abstract)
Background E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific amino-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation (By similarity).

Synonyms: UBR7, C14orf130, Putative E3 ubiquitin-protein ligase UBR7, N-recognin-7
NCBI Accession NP_786924
UniProt Q8N806
Application Notes WB: 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.36 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Supplier Images
Western Blotting (WB) image for anti-Ubiquitin Protein Ligase E3 Component N-Recognin 7 (Putative) (UBR7) (AA 100-128), (N-Term) antibody (ABIN1881973) UBR7 Antibody (N-term) (ABIN1881973) western blot analysis in MDA-MB231 cell line lys...
Product cited in: Lee, Pal, Tasaki, Roy, Jiang, An, Banerjee, Kwon: "Synthetic heterovalent inhibitors targeting recognition E3 components of the N-end rule pathway." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 1, pp. 100-5, 2008 (PubMed).

Kiechl, Werner, Knoflach, Furtner, Willeit, Schett: "The osteoprotegerin/RANK/RANKL system: a bone key to vascular disease." in: Expert review of cardiovascular therapy, Vol. 4, Issue 6, pp. 801-11, 2006 (PubMed).