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  • 产品名称：anti-HSPA8antibody(HeatShock70kDaProtein8)(AA539-569)

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简单介绍：
anti-HSPA8antibody(HeatShock70kDaProtein8)(AA539-569)
详情介绍：
Immunogen This HSPA8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 539-569 AA from the C-terminal region of human HSPA8.
Clone RB16528
Isotype Ig
Predicted Reactivity Mouse (Murine),Rat (Meriones),Cow (Bovine),Hamster
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name HSPA8 (HSPA8 Antibody Abstract)
Background HSPA8 belongs to the heat shock protein 70 family which contains both heat-inducible and constitutively expressed members. The latter are called heat-shock cognate proteins. HSPA8 is a heat-shock cognate protein. This protein binds to nascent polypeptides to facilitate correct folding. The protein also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell.
Synonyms: HSPA8, HSC70, HSP73, HSPA10, Heat shock cognate 71 kDa protein, Heat shock 70 kDa protein 8
Molecular Weight 70898 Da
Gene ID 3312
NCBI Accession NP_694881, NP_006588
UniProt P11142
Application Notes WB - 1:1000,IF - 1:10-50,IHC (p) - 1:10-50,FC - 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2.0 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Product cited in: Tsukahara, Yoshioka, Muraki: "Molecular and functional characterization of HSC54, a novel variant of human heat-shock cognate protein 70." in: Molecular pharmacology, Vol. 58, Issue 6, pp. 1257-63, 2000 (PubMed).

Egerton, Moritz, Druker, Kelso, Simpson: "Identification of the 70kD heat shock cognate protein (Hsc70) and alpha-actinin-1 as novel phosphotyrosine-containing proteins in T lymphocytes." in: Biochemical and biophysical research communications, Vol. 224, Issue 3, pp. 666-74, 1996 (PubMed).