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Alternative Name
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ARHGEF1 (ARHGEF1 Antibody Abstract)
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Background
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Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.
Synonyms: Rho guanine nucleotide exchange factor 1,ARHGEF1,
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Research Area
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Phospho-specific antibodies, Protein Modifications, Cell Structure
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Pathways
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Neurotrophin Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling, Thromboxane A2 Receptor Signaling
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