|
Alternative Name
|
NR2E3 (NR2E3 Antibody Abstract)
|
|
Background
|
This protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. Nuclear receptors have been shown to regulate pathways involved in embryonic development, as well as in maintenance of proper cell function in *****s. Members of this family are characterized by discrete domains that function in DNA and ligand binding. This gene encodes a retinal nuclear receptor that is a ligand-dependent transcription factor. Defects in this gene are a cause of enhanced S cone syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
Synonyms: Photoreceptor-specific nuclear receptor,NR2E3,PNR, RNR
|
|
Molecular Weight
|
44692 DA
|
|
Gene ID
|
10002
|
|
NCBI Accession
|
NP_057430, NP_055064
|
|
UniProt
|
Q9Y5X4
|
|
Research Area
|
Ubiquitin-related antibodies, Phospho-specific antibodies, Cell Signaling, Protein Modifications, Transcription Factors, Signaling, Neurology, Cell Structure
|
|
Pathways
|
Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
|
