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  • 产品名称：anti-Leucine-RichRepeatsandCalponinHomology(CH)DomainContaining1(LRCH1)(AA304-3

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简单介绍：
anti-Leucine-RichRepeatsandCalponinHomology(CH)DomainContaining1(LRCH1)(AA304-333),(Center)antibody
详情介绍：
Immunogen This LRCH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 304-333 amino acids from the Central region of human LRCH1.
Clone RB42699
Predicted Reactivity Mouse (Murine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Alternative Name LRCH1 (LRCH1 Antibody Abstract)
Background This gene encodes a protein with a leucine-rich repeat and a calponin homology domain. Polymorphism in this gene may be associated with susceptibililty to knee osteoarthritis. Alternative splicing results in multiple transcript variants encoding different isoforms.

Synonyms: LRCH1, CHDC1, KIAA1016, Leucine-rich repeat and calponin homology domain-containing protein 1, Calponin homology domain-containing protein 1, Neuronal protein 81
NCBI Accession NP_001157685, NP_055931, NP_001157683
UniProt Q9Y2L9
Application Notes WB: 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.48 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Supplier Images
Western Blotting (WB) image for anti-Leucine-Rich Repeats and Calponin Homology (CH) Domain Containing 1 (LRCH1) (AA 304-333), (Center) antibody (ABIN1881505) LRCH1 Antibody (Center) (ABIN1881505) western blot analysis in Hela cell line lysates...
Product cited in: Zintzaras, Kitsios, Ziogas, Rodopoulou, Karachalios: "Field synopsis and synthesis of genetic association studies in osteoarthritis: the CUMAGAS-OSTEO information system." in: American journal of epidemiology, Vol. 171, Issue 8, pp. 851-8, 2010 (PubMed).

Jiang, Shi, Nakajima, Dai, Wei, Malizos, Qin, Miyamoto, Kamatani, Liu, Tsezou, Nakamura, Ikegawa: "Lack of association of single nucleotide polymorphism in LRCH1 with knee osteoarthritis susceptibility." in: Journal of human genetics, Vol. 53, Issue 1, pp. 42-7, 2007 (PubMed).

Ikegawa: "New gene associations in osteoarthritis: what do they provide, and where are we going?" in: Current opinion in rheumatology, Vol. 19, Issue 5, pp. 429-34, 2007 (PubMed).

Snelling, Sinsheimer, Carr, Loughlin: "Genetic association analysis of LRCH1 as an osteoarthritis susceptibility locus." in: Rheumatology (Oxford, England), Vol. 46, Issue 2, pp. 250-2, 2007 (PubMed).

Spector, Reneland, Mah, Valdes, Hart, Kammerer, Langdown, Hoyal, Atienza, Doherty, Rahman, Nelson, Braun: "Association between a variation in LRCH1 and knee osteoarthritis: a genome-wide single-nucleotide polymorphism association study using DNA pooling." in: Arthritis and rheumatism, Vol. 54, Issue 2, pp. 524-32, 2006 (PubMed).