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  • 产品名称:anti-RNABindingMotifProtein,Y-LinkedFamily1MemberA1(RBMY1A1)(AA468-496),(C-Term

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简单介绍:
anti-RNABindingMotifProtein,Y-LinkedFamily1MemberA1(RBMY1A1)(AA468-496),(C-Term)antibody
详情介绍:
Immunogen This RBMY1A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 468-496 amino acids from the C-terminal region of human RBMY1A1.
Clone RB41568
Purification This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Alternative Name RBMY1A1 (RBMY1A1 Antibody Abstract)
Background This gene encodes a protein containing an RNA-binding motif in the N-terminus and four SRGY (serine, arginine, glycine, tyrosine) boxes in the C-terminus. Multiple copies of this gene are found in the AZFb azoospermia factor region of chromosome Y and the encoded protein is thought to be involved in spermatogenesis. Most copies of this locus are pseudogenes, although six highly similar copies have full-length ORFs and are considered functional. Four functional copies of this gene are found within inverted repeat IR2, two functional copies of this gene are found in palindrome P3, along with two copies of PTPN13-like, Y-linked. [provided by RefSeq].

Synonyms: RBMY1A1,RNA-binding motif protein, Y chromosome, family 1 member A1/C,RBM1, RBM2, YRRM1
NCBI Accession NP_005049
UniProt P0DJD3
Research Area Reproduction, Chromatin Binding Proteins, DNA/RNA
Application Notes WB: 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.36 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Supplier Images
Western Blotting (WB) image for anti-RNA Binding Motif Protein, Y-Linked Family 1 Member A1 (RBMY1A1) (AA 468-496), (C-Term) antibody (ABIN1881734) RBMY1A1 Antibody (C-term) (ABIN1881734) western blot analysis in NCI-H292 cell line l...
Product cited in: Dreumont, Bourgeois, Lejeune, Liu, Ehrmann, Elliott, Stévenin: "Human RBMY regulates germline-specific splicing events by modulating the function of the serine/arginine-rich proteins 9G8 and Tra2-{beta}." in: Journal of cell science, Vol. 123, Issue Pt 1, pp. 40-50, 2009 (PubMed).

Skrisovska, Bourgeois, Stefl, Grellscheid, Kister, Wenter, Elliott, Stevenin, Allain: "The testis-specific human protein RBMY recognizes RNA through a novel mode of interaction." in: EMBO reports, Vol. 8, Issue 4, pp. 372-9, 2007 (PubMed).

Lavery, Glennon, Houghton, Nolan, Egan, Maher: "Investigation of DAZ and RBMY1 gene expression in human testis by quantitative real-time PCR." in: Archives of andrology, Vol. 53, Issue 2, pp. 71-3, 2007 (PubMed).