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  • 产品名称：anti-LIG1antibody(LigaseI,DNA,ATP-Dependent)(AA1-30)

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简单介绍：
anti-LIG1antibody(LigaseI,DNA,ATP-Dependent)(AA1-30)
详情介绍：
Immunogen This LIG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 AA from the N-terminal region of human LIG1.
Clone RB34576
Isotype Ig
Specificity This LIG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human LIG1.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name LIG1 (LIG1 Antibody Abstract)
Background LIG1 encodes DNA ligase I, with functions in DNA replication and the base excision repair process. Mutations in LIG1 that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents.
Synonyms: DNA ligase 1,LIG1,
Research Area Ubiquitin-related antibodies, Phospho-specific antibodies, Protein Modifications, Signaling, Chromatin, Cell Structure
Pathways Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Supplier Images
Western Blotting (WB) image for anti-Ligase I, DNA, ATP-Dependent (LIG1) (AA 1-30), (N-Term) antibody (ABIN658750) LIG1 Antibody (N-term) (ABIN658750) western blot analysis in CEM cell line lysates (3...
Background publications Guillem, Cervantes, Martínez, Alvarez-Larrán, Collado, Camós, Sureda, Maffioli, Marugán, Hernández-Boluda: "XPC genetic polymorphisms correlate with the response to imatinib treatment in patients with chronic phase chronic myeloid leukemia." in: American journal of hematology, Vol. 85, Issue 7, pp. 482-6, 2010 (PubMed).