anti-GDF15antibody(GrowthDifferentiationFactor15)(AA51-79) 抗体网

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产品名称：anti-GDF15antibody(GrowthDifferentiationFactor15)(AA51-79)
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anti-GDF15antibody(GrowthDifferentiationFactor15)(AA51-79)

详情介绍：

Product Details anti-GDF15 Antibody
Product Details anti-GDF15 Antibody
Immunogen	This GDF15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-79 AA from the N-terminal region of human GDF15.
Clone	RB30209
Isotype	Ig
Specificity	This GDF15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-79 amino acids from the N-terminal region of human GDF15.
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.

Target Details GDF15
Target Details GDF15
Alternative Name	GDF15 (GDF15 Antibody Abstract)
Background	Bone morphogenetic proteins (e.g., BMP9, MIM 605120) are members of the transforming growth factor-beta (see TGFB1, MIM 190180) superfamily and regulate tissue differentiation and maintenance. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein. Synonyms: Growth/differentiation factor 15,GDF15,MIC1, PDF, PLAB, PTGFB
Research Area	Cell Signaling, Protein Modifications, Cell Cycle, Cell Structure

Application Details
Application Details
Application Notes	WB = 1:1000, IHC (p) = 1:10-50, FACS = 1:10-50
Restrictions	For Research Use only

Handling
Handling
Format	Liquid
Concentration	0.4 mg/mL
Buffer	PBS with 0.09 % (W/V) sodium azide
Preservative	Sodium azide
Precaution of Use	This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Images
Images
Supplier Images	GDF15 Antibody (N-term) western blot analysis in NCI-H460 cell line lysates (35ug/la... GDF15 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin ... GDF15 Antibody (N-term) flow cytometric analysis of NCI-H460 cells (right histogram)... Images for product: anti-Growth Differentiation Factor 15 (GDF15) (AA 51-79), (N-Term) antibody GDF15 Antibody (N-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the GDF15 antibody detected the GDF15 protein (arrow). GDF15 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GDF15 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. GDF15 Antibody (N-term) flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

References for anti-GDF15 antibody (ABIN656484)
References for anti-GDF15 antibody (ABIN656484)
Background publications	Roth, Junker, Tritschler, Mittelbronn, Dombrowski, Breit, Tabatabai, Wick, Weller, Wischhusen: "GDF-15 contributes to proliferation and immune escape of malignant gliomas." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 16, Issue 15, pp. 3851-9, 2010 (PubMed).