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  • 产品名称：anti-BTKantibody(BrutonAgammaglobulinemiatyrosineKinase)(AA27-55)

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简单介绍：
anti-BTKantibody(BrutonAgammaglobulinemiatyrosineKinase)(AA27-55)
详情介绍：
Immunogen This BTK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-55 AA from the N-terminal region of human BTK.
Clone RB33691
Isotype Ig
Specificity This BTK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-55 amino acids from the N-terminal region of human BTK.
Predicted Reactivity Chicken,Mouse (Murine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name BTK (BTK Antibody Abstract)
Background The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement.
Synonyms: Tyrosine-protein kinase BTK,BTK,AGMX1, ATK, BPK
Molecular Weight 76281 DA
Gene ID 695
NCBI Accession NP_000052
UniProt Q06187
Research Area Ubiquitin-related antibodies, Signaling, Phospho-specific antibodies, Cell Signaling, Cell Structure, Protein Modifications, Chromatin
Pathways Fc-epsilon Receptor Signaling Pathway, Hormone Transport, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades
Application Notes WB = 1:1000, IHC (p) = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment BTK Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Bruton Agammaglobulinemia tyrosine Kinase (BTK) (AA 27-55), (N-Term) antibody (ABIN657469) Western blot analysis of BTK (arrow) using rabbit polyclonal BTK Antibody (N-term) (A...