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  • 产品名称：anti-ABCC12antibody(ATP-BindingCassette,Sub-FamilyC(CFTR/MRP),Member12)(AA723-7

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简单介绍：
anti-ABCC12antibody(ATP-BindingCassette,Sub-FamilyC(CFTR/MRP),Member12)(AA723-752)
详情介绍：
Immunogen This ABCC12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 723-752 AA from the Central region of human ABCC12.
Clone RB32878
Isotype Ig
Specificity This ABCC12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 722-751 amino acids from the Central region of human ABCC12.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name ABCC12 (ABCC12 Antibody Abstract)
Background This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer.
Synonyms: Multidrug resistance-associated protein 9,ABCC12,MRP9
Research Area Protein Modifications, Cell Structure, Signaling, Chromatin
Application Notes WB = 1:1000, IHC (p) = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Supplier Images
Immunohistochemistry (IHC) image for anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 12 (ABCC12) (AA 723-752), (Center) antibody (ABIN657120) ABCC12 Antibody (Center) (ABIN657120) immunohistochemistry analysis in formalin fixed...
Background publications Rose, Behm, Drgon, Johnson, Uhl: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010 (PubMed).

Yabuuchi, Shimizu, Takayanagi, Ishikawa: "Multiple splicing variants of two new human ATP-binding cassette transporters, ABCC11 and ABCC12." in: Biochemical and biophysical research communications, Vol. 288, Issue 4, pp. 933-9, 2001 (PubMed).