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  • 产品名称:anti-gammaGlutamyltransferase1(GGT1)(AA12-39),(N-Term)antibody

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简单介绍:
anti-gammaGlutamyltransferase1(GGT1)(AA12-39),(N-Term)antibody
详情介绍:
Immunogen This Rat Ggt1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-39 amino acids from the N-terminal region of rat Ggt1.
Clone RB40721
Purification This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Alternative Name Ggt1 (GGT1 Antibody Abstract)
Background Initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracelular GSH level. It is part of the cell antioxidant defense mechanism. Catalyzes the transfer of the glutamyl moiety of glutathione to amino acids and dipeptide acceptors. Alternatively, glutathione can be hydrolyzed to give Cys-Gly and gamma glutamate.

Synonyms: Ggt1, Ggt, Gamma-glutamyltranspeptidase 1, Gamma-glutamyltransferase 1, Glutathione hydrolase 1, Leukotriene-C4 hydrolase, CD_antigen=CD224, Gamma-glutamyltranspeptidase 1 heavy chain, Gamma-glutamyltranspeptidase 1 light chain
NCBI Accession NP_446292
UniProt P07314
Application Notes WB: 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.27 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Supplier Images
Western Blotting (WB) image for anti-gamma Glutamyltransferase 1 (GGT1) (AA 12-39), (N-Term) antibody (ABIN1881372) Rat Ggt1 Antibody (N-term) (ABIN1881372) western blot analysis in mouse liver tissue ...
Product cited in: Aly, Lightfoot, El-Shemy: "Modulatory role of lipoic acid on lipopolysaccharide-induced oxidative stress in ***** rat Sertoli cells in vitro." in: Chemico-biological interactions, Vol. 182, Issue 2-3, pp. 112-8, 2009 (PubMed).

Hamden, Carreau, Ellouz, Masmoudi, El: "Protective effect of 17beta-estradiol on oxidative stress and liver dysfunction in aged male rats." in: Journal of physiology and biochemistry, Vol. 63, Issue 3, pp. 195-201, 2008 (PubMed).

Pandur, Pankiv, Johannessen, Moens, Huseby: "Gamma-glutamyltransferase is upregulated after oxidative stress through the Ras signal transduction pathway in rat colon carcinoma cells." in: Free radical research, Vol. 41, Issue 12, pp. 1376-84, 2007 (PubMed).