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  • 产品名称：anti-Ectonucleotidepyrophosphatase/phosphodiesterase3(ENPP3)(AA814-843),(C-Term

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简单介绍：
anti-Ectonucleotidepyrophosphatase/phosphodiesterase3(ENPP3)(AA814-843),(C-Term)antibody
详情介绍：
Immunogen This ENPP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 814-843 amino acids from the C-terminal region of human ENPP3.
Clone RB24586
Purification This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Alternative Name ENPP3 (ENPP3 Antibody Abstract)
Background The protein encoded by this gene belongs to a series of ectoenzymes that are involved in hydrolysis of extracellular nucleotides. These ectoenzymes possess ATPase and ATP pyrophosphatase activities and are type II transmembrane proteins. Expression of the related rat mRNA has been found in a subset of immature glial cells and in the alimentary tract. The corresponding rat protein has been detected in the pancreas, small intestine, colon, and liver. The human mRNA is expressed in glioma cells, prostate, and uterus. Expression of the human protein has been detected in uterus, basophils, and mast cells. [provided by RefSeq].

Synonyms: ENPP3, PDNP3, Ectonucleotide pyrophosphatase/phosphodiesterase family member 3, Phosphodiesterase I beta, Phosphodiesterase I/nucleotide pyrophosphatase 3, CD_antigen=CD203c, Alkaline phosphodiesterase I, Nucleotide pyrophosphatase
NCBI Accession NP_005012
UniProt O14638
Research Area Signaling, Metabolism, DNA/RNA
Pathways Regulation of Muscle Cell Differentiation, Negative Regulation of Transporter Activity
Application Notes WB: 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Supplier Images
Western Blotting (WB) image for anti-Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) (AA 814-843), (C-Term) antibody (ABIN1881297) ENPP3 Antibody (C-term) (ABIN1881297) western blot analysis in MDA-MB453 cell line ly...
Product cited in: Ono, Taniguchi, Higashi, Mita, Kajiwara, Yamaguchi, Tatsuno, Fukutomi, Tanimoto, Sekiya, Oshikata, Tsuburai, Tsurikisawa, Otomo, Maeda, Hasegawa, Miyazaki, Kumamoto, Akiyama: "CD203c expression on human basophils is associated with asthma exacerbation." in: The Journal of allergy and clinical immunology, Vol. 125, Issue 2, pp. 483-489.e3, 2010 (PubMed).

Wolanczyk-Medrala, Barg, Gogolewski, Panaszek, Liebhart, Litwa, Medrala: "Influence of hyperosmotic conditions on basophil CD203c upregulation in patients with food-dependent exercise-induced anaphylaxis." in: Annals of agricultural and environmental medicine : AAEM, Vol. 16, Issue 2, pp. 301-4, 2010 (PubMed).

Chirumbolo, Brizzi, Ortolani, Vella, Bellavite: "Inhibition of CD203c membrane up-regulation in human basophils by high dilutions of histamine: a controlled replication study." in: Inflammation research : official journal of the European Histamine Research Society ... [et al.], Vol. 58, Issue 11, pp. 755-64, 2009 (PubMed).

Hanna, Kruskal, Ezekowitz, Bloom, Collier: "Role of macrophage oxidative burst in the action of anthrax lethal toxin." in: Molecular medicine (Cambridge, Mass.), Vol. 1, Issue 1, pp. 7-18, 1996 (PubMed).