anti-Cystathionine-beta-Synthase(CBS)(AA104-133),(N-Term)antibody 抗体网

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产品名称：anti-Cystathionine-beta-Synthase(CBS)(AA104-133),(N-Term)antibody
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产品厂商：半导体
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简单介绍：

anti-Cystathionine-beta-Synthase(CBS)(AA104-133),(N-Term)antibody

详情介绍：

Product details
Product details
Immunogen	This CBS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-133 amino acids from the N-terminal region of human CBS.
Clone	RB22961
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Target details
Target details
Alternative Name	CBS (CBS Antibody Abstract)
Background	CBS acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. This protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. Synonyms: CBS, Cystathionine beta-synthase, Beta-thionase, Serine sulfhydrase
NCBI Accession	NP_000062, NP_001171480, NP_001171479
UniProt	P35520
Research Area	Signaling, Metabolism, Amino Acids

Application Details
Application Details
Application Notes	WB: 1:1000,IHC (p): 1:50-100,FACS: 1:10-50,IF: 1:10-50
Restrictions	For Research Use only

Handling
Handling
Format	Liquid
Concentration	0.38 mg/mL
Buffer	Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative	Sodium azide
Precaution of Use	WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Images
Images
Supplier Images	CBS Antibody (N-term) (ABIN1881141) flow cytometric analysis of Ramos cells (bottom h... CBS Antibody (N-term) (ABIN1881141) flow cytometric analysis of Ramos cells (bottom h... CBS Antibody (N-term) (ABIN1881141) flow cytometric analysis of Ramos cells (bottom h... CBS Antibody (N-term) (ABIN1881141) flow cytometric analysis of Ramos cells (bottom h... CBS Antibody (N-term) (ABIN1881141) flow cytometric analysis of Ramos cells (bottom h... Images for product: anti-Cystathionine-beta-Synthase (CBS) (AA 104-133), (N-Term) antibody CBS Antibody (N-term) (ABIN1881141) flow cytometric analysis of Ramos cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. CBS Antibody (N-term) (ABIN1881141) flow cytometric analysis of Ramos cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. CBS Antibody (N-term) (ABIN1881141) flow cytometric analysis of Ramos cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. CBS Antibody (N-term) (ABIN1881141) flow cytometric analysis of Ramos cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. CBS Antibody (N-term) (ABIN1881141) flow cytometric analysis of Ramos cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

References
References
Product cited in:	Lee, Feliers, Mariappan, Sataranatarajan, Choudhury, Gorin, Kasinath: "Tadalafil Integrates Nitric Oxide-Hydrogen Sulfide Signaling to Inhibit High Glucose-induced Matrix Protein Synthesis in Podocytes." in: The Journal of biological chemistry, Vol. 290, Issue 19, pp. 12014-26, 2015 (PubMed). Lee, Mariappan, Feliers, Cavaglieri, Sataranatarajan, Abboud, Choudhury, Kasinath: "Hydrogen sulfide inhibits high glucose-induced matrix protein synthesis by activating AMP-activated protein kinase in renal epithelial cells." in: The Journal of biological chemistry, Vol. 287, Issue 7, pp. 4451-61, 2012 (PubMed).