anti-ApolipoproteinA-II(APOA2)(AA28-56),(Center)antibody 抗体网

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产品名称：anti-ApolipoproteinA-II(APOA2)(AA28-56),(Center)antibody
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产品厂商：半导体
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简单介绍：

anti-ApolipoproteinA-II(APOA2)(AA28-56),(Center)antibody

详情介绍：

Product details
Product details
Immunogen	This APOA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-56 amino acids from the Central region of human APOA2.
Clone	RB15149
Predicted Reactivity	Monkey
Purification	This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. Purified Rabbit Polyclonal Antibody (Pab)

Target details
Target details
Alternative Name	APOA2 (APOA2 Antibody Abstract)
Background	APOA2, apolipoprotein (apo-) A-II, which is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia. Synonyms: Apolipoprotein A-II, Apo-AII, ApoA-II, Apolipoprotein A-II(1-76), APOA2
NCBI Accession	NP_001634
UniProt	P02652
Pathways	Regulation of Lipid Metabolism by PPARalpha, Production of Molecular Mediator of Immune Response, Negative Regulation of Transporter Activity

Application Details
Application Details
Application Notes	IHC (p): 1:10-50
Restrictions	For Research Use only

Handling
Handling
Format	Liquid
Concentration	2 mg/mL
Buffer	Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative	Sodium azide
Precaution of Use	WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Images
Images
Supplier Images	Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with APOA2 ... Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with APOA2 antibody (Center) (ABIN1882063), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated. Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with APOA2 antibody (Center) (ABIN1882063), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated.

References
References
Product cited in:	Duesing, Charpentier, Marre, Tichet, Hercberg, Balkau, Froguel, Gibson: "Evaluating the association of common APOA2 variants with type 2 diabetes." in: BMC medical genetics, Vol. 10, pp. 13, 2009 (PubMed). Atta, Crook, Shafique, Johnston, Godsland: "Procoagulant activities of plasma factor VIIc and factor Xc are positively and independently associated with concentrations of the high-density lipoprotein apolipoprotein, apo A-II." in: Thrombosis and haemostasis, Vol. 100, Issue 3, pp. 391-6, 2008 (PubMed).