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  • 产品名称：anti-HNRNPH1antibody(HeterogeneousNuclearRibonucleoproteinH1(H))(AA48-77)

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简单介绍：
anti-HNRNPH1antibody(HeterogeneousNuclearRibonucleoproteinH1(H))(AA48-77)
详情介绍：
Immunogen This HNRNPH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-77 amino acids from the N-terminal region of human HNRNPH1.
Clone RB42336
Predicted Reactivity Cow (Bovine),Mouse (Murine),Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Alternative Name HNRNPH1 (HNRNPH1 Antibody Abstract)
Background This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. It is very similar to the family member HNRPF. This gene is thought to be potentially involved in hereditary lymphedema type I phenotype. [provided by RefSeq].

Synonyms: HNRNPH1, HNRPH, HNRPH1, Heterogeneous nuclear ribonucleoprotein H, Heterogeneous nuclear ribonucleoprotein H, N-terminally processed
NCBI Accession NP_001244222, NP_005511
UniProt P31943
Application Notes WB: 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Supplier Images
Western Blotting (WB) image for anti-Heterogeneous Nuclear Ribonucleoprotein H1 (H) (HNRNPH1) (AA 48-77), (N-Term) antibody (ABIN1881424) HNRNPH1 Antibody (N-term) (ABIN1881424) western blot analysis in NCI-H292 cell line l...
Product cited in: Van Dusen, Yee, McNally, McNally: "A glycine-rich domain of hnRNP H/F promotes nucleocytoplasmic shuttling and nuclear import through an interaction with transportin 1." in: Molecular and cellular biology, Vol. 30, Issue 10, pp. 2552-62, 2010 (PubMed).

Rauch, ONeill, Mack, Matthias, Munz, Kolch, Gires: "Heterogeneous nuclear ribonucleoprotein H blocks MST2-mediated apoptosis in cancer cells by regulating A-Raf transcription." in: Cancer research, Vol. 70, Issue 4, pp. 1679-88, 2010 (PubMed).

Fisette, Toutant, Dugré-Brisson, Desgroseillers, Chabot: "hnRNP A1 and hnRNP H can collaborate to modulate 5' splice site selection." in: RNA (New York, N.Y.), Vol. 16, Issue 1, pp. 228-38, 2009 (PubMed).