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  • 产品名称：anti-CNBPantibody(CCHC-TypeZincFinger,NucleicAcidBindingProtein)(AA91-118)

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简单介绍：
anti-CNBPantibody(CCHC-TypeZincFinger,NucleicAcidBindingProtein)(AA91-118)
详情介绍：
Immunogen This CNBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-118 amino acids from the Central region of human CNBP.
Clone RB43101
Predicted Reactivity Cow (Bovine),Chicken,Mouse (Murine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Alternative Name CNBP (CNBP Antibody Abstract)
Background This gene encodes a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. The protein functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion in the first intron of this gene results in myotonic dystrophy type 2. Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms: CNBP, RNF163, ZNF9, Cellular nucleic acid-binding protein, Zinc finger protein 9
NCBI Accession NP_003409, NP_001120668, NP_001120664, NP_001120666, NP_001120665
UniProt P62633
Application Notes WB: 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Supplier Images
Western Blotting (WB) image for anti-CCHC-Type Zinc Finger, Nucleic Acid Binding Protein (CNBP) (AA 91-118), (Center) antibody (ABIN1881216) CNBP Antibody (Center) (ABIN1881216) western blot analysis in MCF-7 cell line and rat...
Product cited in: Catalli, Morgante, Iraci, Rinaldi, Botta, Novelli: "Validation of sensitivity and specificity of tetraplet-primed PCR (TP-PCR) in the molecular diagnosis of myotonic dystrophy type 2 (DM2)." in: The Journal of molecular diagnostics : JMD, Vol. 12, Issue 5, pp. 601-6, 2010 (PubMed).

Massa, Panico, Caldarola, Fusco, Sabatelli, Terracciano, Botta, Novelli, Bernardi, Loreni: "The myotonic dystrophy type 2 (DM2) gene product zinc finger protein 9 (ZNF9) is associated with sarcomeres and normally localized in DM2 patients' muscles." in: Neuropathology and applied neurobiology, Vol. 36, Issue 4, pp. 275-84, 2010 (PubMed).

Auvinen, Suominen, Hannonen, Bachinski, Krahe, Udd: "Myotonic dystrophy type 2 found in two of sixty-three persons diagnosed as having fibromyalgia." in: Arthritis and rheumatism, Vol. 58, Issue 11, pp. 3627-31, 2008 (PubMed).

Panayiotopoulos, Scarpalezos: "Dystrophia myotonica. Peripheral nerve involvement and pathogenetic implications." in: Journal of the neurological sciences, Vol. 27, Issue 1, pp. 1-16, 1976 (PubMed).