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  • 产品名称：anti-ALPantibody(AlkalinePhosphatase,Placental)(AA56-83)

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简单介绍：
anti-ALPantibody(AlkalinePhosphatase,Placental)(AA56-83)
详情介绍：
Immunogen This ALPP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-83 AA from the N-terminal region of human ALPP.
Clone RB35524
Isotype Ig
Specificity This ALPP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-83 amino acids from the N-terminal region of human ALPP.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name ALPP (ALP Antibody Abstract)
Background There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form. The coding sequence for this form of alkaline phosphatase is unique in that the 3' untranslated region contains multiple copies of an Alu family repeat. In addition, this gene is polymorphic and three common alleles (type 1, type 2 and type 3) for this form of alkaline phosphatase have been well characterized.
Synonyms: Alkaline phosphatase, placental type,ALPP,PLAP
Research Area Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Structure, Metabolism
Application Notes WB = 1:1000, IHC (p) = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Supplier Images
Western Blotting (WB) image for anti-Alkaline Phosphatase, Placental (ALP) (AA 56-83), (N-Term) antibody (ABIN658854) Western blot analysis of ALPP (arrow) using rabbit polyclonal ALPP Antibody (N-term) ...
Background publications Estrada, Krawczak, Schreiber, van Duijn, Stolk, van Meurs, Liu, Penninx, Smit, Vogelzangs, Hottenga, Willemsen, de Geus, Lorentzon, von Eller-Eberstein, Lips, Schoor, Pop, de Keijzer, Hofman, Aulchenko, Oostra, Ohlsson, Boomsma, Uitterlinden, van Duijn, R: "A genome-wide association study of northwestern Europeans involves the C-type natriuretic peptide signaling pathway in the etiology of human height variation." in: Human molecular genetics, Vol. 18, Issue 18, pp. 3516-24, 2009 (PubMed).