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  • 产品名称：RingFingerProtein216(RNF216)(N-Term)Peptide

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  • 产品厂商：半导体
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简单介绍：
RingFingerProtein216(RNF216)(N-Term)Peptide
详情介绍：
Blocked Antibody anti-RNF216 antibody (Ring Finger Protein 216) (N-Term) (ABIN2774202)
Sequence IVNPRLEQKV IILGENGLLF PESEPLEVQN QSSEDSETEL LSNPGEPAAS
Characteristics This is a synthetic peptide designed for use in combination with anti-Rnf216 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Purification Purified
Background Rnf216 acts as an E3 ubiquitin ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. It promotes degradation of TRAF3, TLR4 and TLR9. It contributes to the regulation of antiviral responses. It down-regulates activation of NF-kappa-B, IRF3 activation and IFNB production and promotes TNF and RIP mediated apoptosis.

Protein Size: 853
Molecular Weight 93 kDa
Gene ID 108086
UniProt P58283
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Concentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handling Advice Avoid repeat freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.