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  • 产品名称：Sirtuin7(SIRT7)(MiddleRegion)Peptide

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  • 产品厂商：半导体
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简单介绍：
Sirtuin7(SIRT7)(MiddleRegion)Peptide
详情介绍：
Blocked Antibody anti-Sirtuin 7 (SIRT7) (Middle Region) antibody (ABIN2779622)
Characteristics This is a synthetic peptide designed for use in combination with anti-SIRT7 antibody (Catalog #: ARP32405_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Purification Purified
Background SIRT7 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. SIRT7 is included in class IV of the sirtuin family. This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.

Alias Symbols: MGC126840, MGC126842, SIR2L7

Protein Interaction Partner: MAGED1,MAGED1

Protein Size: 400
Molecular Weight 45 kDa
Gene ID 51547
NCBI Accession NM_016538, NP_057622
UniProt Q9NRC8
Research Area Chromatin Binding Proteins, Proteases, Transcription Factors, Cancer
Application Notes Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Concentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.