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  • 产品名称：alphaKetoglutarateDehydrogenase(alphaKGDHC)(N-Term)Peptide

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  • 产品厂商：半导体
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简单介绍：
alphaKetoglutarateDehydrogenase(alphaKGDHC)(N-Term)Peptide
详情介绍：
Blocked Antibody anti-alpha Ketoglutarate Dehydrogenase (alphaKGDHC) (N-Term) antibody (ABIN2787780)
Characteristics This is a synthetic peptide designed for use in combination with anti-OGDH antibody (Catalog #: ARP58648_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Purification Purified
Background The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO2. It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3).This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitocondrial matrix and uses thiamine pyrophosphate as a cofactor. A congential deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia.

Alias Symbols: AKGDH, E1k, OGDC

Protein Interaction Partner: DLD,DLST,PLSCR1,DLD,DLST,PLSCR1,USP13

Protein Size: 427
Molecular Weight 47 kDa
Gene ID 4967
NCBI Accession NM_001003941, NP_001003941
UniProt Q96DD3
Research Area Signaling, Metabolism
Application Notes Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Concentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.