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  • 产品名称：YOD1OTUDeubiquinatingEnzyme1Homolog(S.Cerevisiae)(YOD1)(N-Term)Peptide

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简单介绍：
YOD1OTUDeubiquinatingEnzyme1Homolog(S.Cerevisiae)(YOD1)(N-Term)Peptide
详情介绍：
Blocked Antibody anti-YOD1 antibody (YOD1 OTU Deubiquinating Enzyme 1 Homolog (S. Cerevisiae)) (N-Term) (ABIN2790891)
Sequence VPQSEAGTKA GPAGGRPADT MWRVRCKAKG GTHLLQGLSS RTRLRELQGQ
Characteristics This is a synthetic peptide designed for use in combination with anti-Yod1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Purification Purified
Background Hydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. Yod1 may act by triming the ubiquitin chain on the associated substrate to facilitate their threading through the VCP/p97 pore. Ubiquitin moieties on substrates may present a steric impediment to the threading process when the substrate is transferred to the VCP pore and threaded through VCP's axial channel. Yod1 mediates deubiquitination of both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. It is able to cleave both polyubiquitin and di-ubiquitin.

Alias Symbols: 9930028C20Rik, Hshin7

Protein Size: 343
Molecular Weight 37 kDa
Gene ID 226418
NCBI Accession NM_178691, NP_848806
UniProt Q8CB27
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Concentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handling Advice Avoid repeat freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.