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  • 产品名称：PairedBox7(PAX7)Peptide

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  • 产品厂商：半导体
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简单介绍：
PairedBox7(PAX7)Peptide
详情介绍：
Blocked Antibody anti-PAX7 antibody (Paired Box 7) (C-Term) (ABIN2777560)
Sequence QADFSISPLH GGLDSATSIS ASCSQRADSI KPGDSLPTSQ AYCPPTYSTT
Characteristics This is a synthetic peptide designed for use in combination with anti-PAX7 antibody (Catalog #: ARP32742_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Purification Purified
Background PAX7 is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box gene 7 is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Alternative splicing in this gene has produced two known products but the biological significance of the variants is unknown.

Alias Symbols: FLJ37460, HUP1, PAX7B, RMS2

Protein Interaction Partner: HIRA,UBC,Ubc

Protein Size: 520
Molecular Weight 57 kDa
Gene ID 5081
NCBI Accession NM_002584, NP_002575
UniProt P23759
Research Area Lineage Markers, Transcription Factors, Organogenesis
Application Notes Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Concentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Product cited in: Wehling-Henricks, Li, Lindsey, Wang, Welc, Ramos, Khanlou, Kuro-O, Tidball: "Klotho gene silencing promotes pathology in the mdx mouse model of Duchenne muscular dystrophy." in: Human molecular genetics, Vol. 25, Issue 12, pp. 2465-2482, 2016 (PubMed).