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  • 产品名称：NuclearFactorofkappaLightPolypeptideGeneEnhancerinB-CellsInhibitor,alpha(NFKBIA

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简单介绍：
NuclearFactorofkappaLightPolypeptideGeneEnhancerinB-CellsInhibitor,alpha(NFKBIA)(N-Term)Peptide
详情介绍：
Blocked Antibody anti-NFKBIA antibody (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha) (N-Term) (ABIN2779315)
Sequence MFQAAERPQE WAMEGPRDGL KKERLLDDRH DSGLDSMKDE EYEQMVKELQ
Characteristics This is a synthetic peptide designed for use in combination with anti-IKBA Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Purification Purified
Background This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.

Alias Symbols: IKBA, MAD-3, NFKBI

Protein Size: 317
Molecular Weight 35 kDa
Gene ID 4792
NCBI Accession NM_020529, NP_065390
UniProt P25963
Application Notes Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Concentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.