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  • 产品名称：Rabbitanti-HumanImmunoglobulinJPolypeptide,LinkerProteinForImmunoglobulinalphaa

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  • 产品厂商：OriGene
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简单介绍：
Rabbitanti-HumanImmunoglobulinJPolypeptide,LinkerProteinForImmunoglobulinalphaandmuPolypeptides(IGJ)(C-Term),(JoiningChain)Antibody
详情介绍：
Immunogen A synthetic peptide derived from near C-terminus of Human J-chain protein.
Specificity This antibody detects Immunoglobulin J chain. Cellular localisation: Cytoplasm.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Immunoaffinity Chromatography
Alternative Name Immunoglobulin J Chain
Background J chain is a small glycopeptide with MW of 15 kDa. It is structurally unrelated to heavy or light chains, but is synthesized by all plasma cells that secrete polymeric immunoglobulins. J chain is linked to IgA and IgM by disulfide bonds, however, it has been detected in IgG- and IgD-containing cells. J chains are present in a large proportion of the immunoglobulin-positive cells in the germinal centers of the tonsils and lymph nodes. B cells discrete J chain at an early stage of differentiation with the expression persisting in those cells destined to produce IgA or IgM.Synonyms: IGCJ, IGJ
Molecular Weight 15 kDa
Gene ID 3512
NCBI Accession NP_653247
UniProt P01591
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Restrictions For Research Use only
Format Liquid
Buffer PBS, pH 7.6 with 1 % BSA and less than 0.1 % Sodium Azide
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!