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产品名称:NuclearReceptorSubfamily4,GroupA,Member2(NR4A2)Peptide
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产品厂商:FabGennix
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简单介绍:
NuclearReceptorSubfamily4,GroupA,Member2(NR4A2)Peptide
详情介绍:
Product details
Product details
Blocked
Antibody
anti-NR4A2 antibody (Nuclear Receptor Subfamily 4, Group A, Member 2) (AA 560-610) (ABIN2746962)
Sequence
CTQGLQRIFY LKLEDLVPPP AIIDKL
Characteristics
Nurr1-selective antibodies were generated against a peptide taken from the human Nurr1 protein. The Nurr1-selective antibodies are affinity purified on an immobilized antigen based affinity matrix, the isolated antibodies were then stabilized in antibody stabilization buffer for long-term storage. The anti-Nurr1-selective antibodies are fully characterized for applications in western blotting and ELISA at the recommended dilutions. The Supplier provides Nurr1 western blot positive control samples in SDS-PAGE sample buffer.
The synthetic peptide was taken from human Nurr1 protein form region corresponding to the AA 566-591 correspondingto aa sequence(CTQGLQRIFYLKLEDLVPPPAIIDKL). The peptides were conserved in several otherspecies. The selected peptide was post-synthetically modified to achieve highest antigenicity before coupling to carrier protein using hetero bifunctional cross linker for immunogenpreparation.
Synonyms: Nuclear receptor subfamily 4 group A member 2, Immediate-early response protein not, Transcriptionally induced nuclear receptor
Purification
Synthetic peptide
Target details
Target details
Background
The nuclear receptor 4 family comprise of NR4A1-NR4A2 and NR4A3 orphan nuclear receptors, their activities are associated with cell proliferation, apoptosis and termainl differentiation in a tissue dependent manner. Structural/functional studies suggest that NR4As are \
UniProt
P43354
Research Area
Cancer, Transcription Factors
Application Details
Application Details
Application Notes
Antibodies were tested in ELISA and western blotting applications at 1:500 dilution using ABIN1686770 samples. Antibody dilutions for these antibodies are for reference only, investigators are expected to determine the optimal conditions. Application of this antibody in other protocols has not yet tested.
WB: > 1:500
IMM & IP pull-down assays: N.D. .
IHC: N.D. .
Investigators using this antibody in protocols other than listed above can request a complimentary sample of this antibody. N.D. not necessarily means the antibody is not suitable for that application, it simply means we have not yet characterized the antibody in that application.
The antibody labels a strong band of Nurr1 of 75 kDa in ABIN1686770 samples and in several cell lines.
Restrictions
For Research Use only
Handling
Handling
Format
Liquid
Storage
-20 °C