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  • 产品名称：anti-Mesothelinantibody(MSLN)

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简单介绍：
anti-Mesothelinantibody(MSLN)
详情介绍：
Immunogen Recombinant protein of human MSLN
Isotype IgG
Purification Antigen affinity purification
Alternative Name MSLN (MSLN Antibody Abstract)
Background This gene encodes a precursor protein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiation factor functions as a cytokine that can stimulate colony formation in bone marrow megakaryocytes. Mesothelian is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants.
Synonyms: MPF, SMRP
Pathways EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Handling Advice Avoid freeze / thaw cycles.
Storage -20 °C/-80 °C
Storage Comment Store at -20°C (regular) and -80°C (long term).
Supplier Images
Immunohistochemistry (IHC) image for anti-Mesothelin (MSLN) antibody (ABIN2421879) Immunohistochemistry of Human lung cancer using MSLN Polyclonal Antibody at dilution ...