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  • 产品名称：anti-Catenin(Cadherin-AssociatedProtein),alpha1,102kDa(CTNNA1)antibody

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简单介绍：
anti-Catenin(Cadherin-AssociatedProtein),alpha1,102kDa(CTNNA1)antibody
详情介绍：
Immunogen Recombinant protein of human CTNNA1
Isotype IgG
Purification Antigen affinity purification
Alternative Name CTNNA1 (CTNNA1 Antibody Abstract)
Background Catenin alpha-1 is a protein that in humans is encoded by the CTNNA1 gene. Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherens junctions components.
Synonyms: CAP102
Pathways Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Maintenance of Protein Location
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Handling Advice Avoid freeze / thaw cycles.
Storage -20 °C/-80 °C
Storage Comment Store at -20°C (regular) and -80°C (long term).
Supplier Images
Immunohistochemistry (IHC) image for anti-Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1) antibody (ABIN2427897) Immunohistochemistry of Human thyroid cancer using CTNNA1 Polyclonal Antibody at dilu...