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  • 产品名称：anti-ANAPC5antibody(AnaphasePromotingComplexSubunit5)

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简单介绍：
anti-ANAPC5antibody(AnaphasePromotingComplexSubunit5)
详情介绍：
Immunogen Recombinant protein of human ANAPC5
Isotype IgG
Purification Antigen affinity purification
Alternative Name ANAPC5 (ANAPC5 Antibody Abstract)
Background This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms: APC5
Pathways M Phase
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Handling Advice Avoid freeze / thaw cycles.
Storage -20 °C/-80 °C
Storage Comment Store at -20°C (regular) and -80°C (long term).
Supplier Images
Immunohistochemistry (IHC) image for anti-Anaphase Promoting Complex Subunit 5 (ANAPC5) antibody (ABIN2422609) Immunohistochemistry of Human liver cancer using ANAPC5 Polyclonal Antibody at diluti...