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  • 产品名称：anti-MYSM1antibody(Myb-Like,SWIRMandMPNDomains1)

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简单介绍：
anti-MYSM1antibody(Myb-Like,SWIRMandMPNDomains1)
详情介绍：
Immunogen Synthetic peptide of human MYSM1
Isotype IgG
Purification Antigen affinity purification
Alternative Name MYSM1 (MYSM1 Antibody Abstract)
Background Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.Component of a large chromatin remodeling complex, at least composed of MYSM1, PCAF, RBM10 and KIF11/TRIP5. Binds histones
Synonyms: 2ADUB, 2A-DUB, RP4-592A1.1
Pathways Chromatin Binding
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Handling Advice Avoid freeze / thaw cycles.
Storage -20 °C/-80 °C
Storage Comment Store at -20°C (regular) and -80°C (long term).
Supplier Images
Immunohistochemistry (IHC) image for anti-Myb-Like, SWIRM and MPN Domains 1 (MYSM1) antibody (ABIN2426715) Immunohistochemistry of Human ovarian cancer using MYSM1 Polyclonal Antibody at dilut...