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  • 产品名称：anti-CHRNA2antibody(CholinergicReceptor,Nicotinic,alpha2(Neuronal))

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  • 产品厂商：国内供应2
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简单介绍：
anti-CHRNA2antibody(CholinergicReceptor,Nicotinic,alpha2(Neuronal))
详情介绍：
Immunogen Synthetic peptide of human CHRNA2
Isotype IgG
Purification Antigen affinity purification
Alternative Name CHRNA2 (CHRNA2 Antibody Abstract)
Background Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels formed by a pentameric arrangement of alpha and beta subunits to create distinct muscle and neuronal receptors. Neuronal receptors are found throughout the peripheral and central nervous system where they are involved in fast synaptic transmission. This gene encodes an alpha subunit that is widely expressed in the brain. The proposed structure for nAChR subunits is a conserved N-terminal extracellular domain followed by three conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region. Mutations in this gene cause autosomal dominant nocturnal frontal lobe epilepsy type 4. Single nucleotide polymorphisms (SNPs) in this gene have been associated with nicotine dependence.
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Handling Advice Avoid freeze / thaw cycles.
Storage -20 °C/-80 °C
Storage Comment Store at -20°C (regular) and -80°C (long term).
Supplier Images
Immunohistochemistry (IHC) image for anti-Cholinergic Receptor, Nicotinic, alpha 2 (Neuronal) (CHRNA2) antibody (ABIN2434462) Immunohistochemistry of Human liver cancer using CHRNA2 Polyclonal Antibody at diluti...