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  • 产品名称：anti-GADD45Bantibody(GrowthArrestandDNA-Damage-Inducible,beta)

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简单介绍：
anti-GADD45Bantibody(GrowthArrestandDNA-Damage-Inducible,beta)
详情介绍：
Immunogen Recombinant protein of human GADD45B
Isotype IgG
Purification Antigen affinity purification
Alternative Name GADD45B (GADD45B Antibody Abstract)
Background This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth.
Synonyms: MYD118, GADD45BETA
Pathways Cell Division Cycle
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Handling Advice Avoid freeze / thaw cycles.
Storage -20 °C/-80 °C
Storage Comment Store at -20°C (regular) and -80°C (long term).
Supplier Images
Immunohistochemistry (IHC) image for anti-Growth Arrest and DNA-Damage-Inducible, beta (GADD45B) antibody (ABIN2423503) Immunohistochemistry of Human brain using GADD45B Polyclonal Antibody at dilution of...