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  • 产品名称:anti-BUB1antibody(BuddingUninhibitedByBenzimidazoles1Homolog(Yeast))

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简单介绍:
anti-BUB1antibody(BuddingUninhibitedByBenzimidazoles1Homolog(Yeast))
详情介绍:
Immunogen Recombinant protein of human BUB1
Isotype IgG
Purification Antigen affinity purification
Alternative Name BUB1 (BUB1 Antibody Abstract)
Background This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants.
Synonyms: BUB1A, BUB1L, hBUB1
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Handling Advice Avoid freeze / thaw cycles.
Storage -20 °C/-80 °C
Storage Comment Store at -20°C (regular) and -80°C (long term).
Supplier Images
Immunohistochemistry (IHC) image for anti-Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1) antibody (ABIN2423021) Immunohistochemistry of Human thyroid cancer using BUB1 Polyclonal Antibody at diluti...