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  • 产品名称：anti-AANATantibody(AralkylamineN-Acetyltransferase)

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简单介绍：
anti-AANATantibody(AralkylamineN-Acetyltransferase)
详情介绍：
Immunogen Recombinant protein of human AANAT
Isotype IgG
Purification Antigen affinity purification
Alternative Name AANAT (AANAT Antibody Abstract)
Background The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms: DSPS, SNAT
Pathways Photoperiodism
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Handling Advice Avoid freeze / thaw cycles.
Storage -20 °C/-80 °C
Storage Comment Store at -20°C (regular) and -80°C (long term).
Supplier Images
Immunohistochemistry (IHC) image for anti-Aralkylamine N-Acetyltransferase (AANAT) antibody (ABIN2422931) Immunohistochemistry of Human brain using AANAT Polyclonal Antibody at dilution of 1:40