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  • 产品名称:anti-STAMantibody(SignalTransducingAdaptorMolecule(SH3DomainandITAMMotif)1)

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简单介绍:
anti-STAMantibody(SignalTransducingAdaptorMolecule(SH3DomainandITAMMotif)1)
详情介绍:
Immunogen Recombinant protein of human STAM
Isotype IgG
Purification Antigen affinity purification
Alternative Name STAM (STAM Antibody Abstract)
Background This gene encodes a member of the signal-transducing adaptor molecule family. These proteins mediate downstream signaling of cytokine receptors and also play a role in ER to Golgi trafficking by interacting with the coat protein II complex. The encoded protein also associates with hepatocyte growth factor-regulated substrate to form the endosomal sorting complex required for transport-0 (ESCRT-0), which sorts ubiquitinated membrane proteins to the ESCRT-1 complex for lysosomal degradation. Alternatively spliced transcript variants have been observed for this gene.
Synonyms: STAM1, STAM-1
Pathways EGFR Signaling Pathway, EGFR Downregulation
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Handling Advice Avoid freeze / thaw cycles.
Storage -20 °C/-80 °C
Storage Comment Store at -20°C (regular) and -80°C (long term).
Supplier Images
Immunohistochemistry (IHC) image for anti-Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM) antibody (ABIN2422753) Immunohistochemistry of Human prostate cancer using STAM Polyclonal Antibody at dilut...