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Background
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This gene encodes a voltage-gated sodium channel which plays a significant role in nociception signaling. Mutations in this gene have been associated with primary erythermalgia, channelopathy-associated insensitivity to pain, and paroxysmal extreme pain disorder. Synonyms: PN1, ETHA, NENA, SFNP, FEB3B, NE-NA, GEFSP7, Nav1.7
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