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  • 产品名称：anti-HACE1antibody(HECTDomainandAnkyrinRepeatContaining,E3UbiquitinProteinLigas

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简单介绍：
anti-HACE1antibody(HECTDomainandAnkyrinRepeatContaining,E3UbiquitinProteinLigase1)
详情介绍：
Immunogen Synthetic peptide of human HACE1
Isotype IgG
Purification Antigen affinity purification
Alternative Name HACE1 (HACE1 Antibody Abstract)
Background HACE1 (HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1), also known as KIAA1320, is a 909 amino acid protein that localizes to both the cytoplasm and the endoplasmic reticulum and contains one HECT domain and six ANK repeats. Expressed in kidney, heart and brain, HACE1 functions as an E3 ubiquitin-protein ligase that interacts with the proteasome and is thought to play a role in protein degradation. HACE1 is downregulated in Wilms tumor, suggesting a possible role in tumor suppression.
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Handling Advice Avoid freeze / thaw cycles.
Storage -20 °C/-80 °C
Storage Comment Store at -20°C (regular) and -80°C (long term).
Supplier Images
Immunohistochemistry (IHC) image for anti-HECT Domain and Ankyrin Repeat Containing, E3 Ubiquitin Protein Ligase 1 (HACE1) antibody (ABIN2434736) Immunohistochemistry of Human gastric cancer using HACE1 Polyclonal Antibody at dilut...