产品详情
所在位置: 首页> 产品目录> 一抗>
查看大图

  • 产品名称：anti-p300antibody(E1ABindingProteinP300)

  • 产品型号：
  • 产品厂商：国内供应2
  • 产品文档：
你添加了1件商品 查看购物车
简单介绍：
anti-p300antibody(E1ABindingProteinP300)
详情介绍：
Immunogen Synthetic peptide of human EP300
Isotype IgG
Purification Antigen affinity purification
Alternative Name EP300 (EP300 Antibody Abstract)
Background This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer.
Synonyms: p300, KAT3B, RSTS2
Pathways p53 Signaling, Notch Signaling, Interferon-gamma Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Regulation of Cell Size
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Handling Advice Avoid freeze / thaw cycles.
Storage -20 °C/-80 °C
Storage Comment Store at -20°C (regular) and -80°C (long term).
Supplier Images
Immunohistochemistry (IHC) image for anti-E1A Binding Protein P300 (EP300) antibody (ABIN2434592) Immunohistochemistry of Human thyroid cancer using EP300 Polyclonal Antibody at dilut...