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  • 产品名称：anti-CyclinD2antibody(CCND2)

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简单介绍：
anti-CyclinD2antibody(CCND2)
详情介绍：
Immunogen Synthetic peptide of human CCND2
Isotype IgG
Purification Antigen affinity purification
Alternative Name CCND2 (CCND2 Antibody Abstract)
Background The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation. High level expression of this gene was observed in ovarian and testicular tumors.
Synonyms: KIAK0002
Pathways Cell Division Cycle, Mitotic G1-G1/S Phases
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Handling Advice Avoid freeze / thaw cycles.
Storage -20 °C/-80 °C
Storage Comment Store at -20°C (regular) and -80°C (long term).
Supplier Images
Immunohistochemistry (IHC) image for anti-Cyclin D2 (CCND2) antibody (ABIN2425745) Immunohistochemistry of Human esophagus cancer using CCND2 Polyclonal Antibody at dil...