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  • 产品名称：anti-NOD2antibody(Nucleotide-BindingOligomerizationDomainContaining2)

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简单介绍：
anti-NOD2antibody(Nucleotide-BindingOligomerizationDomainContaining2)
详情介绍：
Immunogen Synthetic peptide of human NOD2
Isotype IgG
Purification Antigen affinity purification
Alternative Name NOD2 (NOD2 Antibody Abstract)
Background This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome.
Synonyms: CD, ACUG, BLAU, IBD1, NLRC2, NOD2B, CARD15, CLR16.3, PSORAS1
Pathways Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Handling Advice Avoid freeze / thaw cycles.
Storage -20 °C/-80 °C
Storage Comment Store at -20°C (regular) and -80°C (long term).
Supplier Images
Immunohistochemistry (IHC) image for anti-Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) antibody (ABIN2434382) Immunohistochemistry of Human thyroid cancer using NOD2 Polyclonal Antibody at diluti...