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  • 产品名称：anti-SMURF2antibody(SMADSpecificE3UbiquitinProteinLigase2)

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  • 产品厂商：国内供应2
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简单介绍：
anti-SMURF2antibody(SMADSpecificE3UbiquitinProteinLigase2)
详情介绍：
Immunogen Synthetic peptide of human SMURF2
Isotype IgG
Purification Antigen affinity purification
Alternative Name SMURF2 (SMURF2 Antibody Abstract)
Background E3 ubiquitin-protein ligase SMURF2 is an enzyme that in humans is encoded by the SMURF2 gene. E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Interacts with SMAD1 and SMAD7 in order to trigger their ubiquitination and proteasome-dependent degradation. In addition, interaction with SMAD7 activates autocatalytic degradation, which is prevented by interaction with SCYE1. Forms a stable complex with the TGF-beta receptor-mediated phosphorylated SMAD2 and SMAD3.
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Handling Advice Avoid freeze / thaw cycles.
Storage -20 °C/-80 °C
Storage Comment Store at -20°C (regular) and -80°C (long term).
Supplier Images
Immunohistochemistry (IHC) image for anti-SMAD Specific E3 Ubiquitin Protein Ligase 2 (SMURF2) antibody (ABIN2432013) Immunohistochemistry of Human liver cancer using SMURF2 Polyclonal Antibody at diluti...