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  • 产品名称:anti-Integrinbeta7antibody(ITGB7)

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简单介绍:
anti-Integrinbeta7antibody(ITGB7)
详情介绍:
Immunogen Synthetic peptide of human ITGB7
Isotype IgG
Purification Antigen affinity purification
Alternative Name ITGB7 (ITGB7 Antibody Abstract)
Background This gene encodes a protein that is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The encoded protein forms dimers with an alpha4 chain or an alphaE chain and plays a role in leukocyte adhesion. Dimerization with alpha4 forms a homing receptor for migration of lymphocytes to the intestinal mucosa and Peyer's patches. Dimerization with alphaE permits binding to the ligand epithelial cadherin, a calcium-dependent adhesion molecule. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
Pathways Integrin Complex
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Handling Advice Avoid freeze / thaw cycles.
Storage -20 °C/-80 °C
Storage Comment Store at -20°C (regular) and -80°C (long term).
Supplier Images
Immunohistochemistry (IHC) image for anti-Integrin beta 7 (ITGB7) antibody (ABIN2433217) Immunohistochemistry of Human gastric cancer using ITGB7 Polyclonal Antibody at dilut...