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  • 产品名称:anti-NFAT1antibody(NuclearFactorofActivatedT-Cells,Cytoplasmic,Calcineurin-Depe

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简单介绍:
anti-NFAT1antibody(NuclearFactorofActivatedT-Cells,Cytoplasmic,Calcineurin-Dependent2)
详情介绍:
Immunogen Synthetic peptide of human NFATC2
Isotype IgG
Purification Antigen affinity purification
Alternative Name NFATC2 (NFAT1 Antibody Abstract)
Background This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized.
Synonyms: NFAT1, NFATP
Pathways RTK Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, VEGF Signaling
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Handling Advice Avoid freeze / thaw cycles.
Storage -20 °C/-80 °C
Storage Comment Store at -20°C (regular) and -80°C (long term).
Supplier Images
Immunohistochemistry (IHC) image for anti-Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1) antibody (ABIN2431905) Immunohistochemistry of Human ovarian cancer using NFATC2 Polyclonal Antibody at dilu...