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  • 产品名称:anti-LTBantibody(Lymphotoxinbeta(TNFSuperfamily,Member3))

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简单介绍:
anti-LTBantibody(Lymphotoxinbeta(TNFSuperfamily,Member3))
详情介绍:
Immunogen Synthetic peptide of human LTB
Isotype IgG
Purification Antigen affinity purification
Alternative Name LTB (LTB Antibody Abstract)
Background Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1?Molecule alpha/2?Molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms.
Synonyms: p33, TNFC, TNFSF3
Pathways NF-kappaB Signaling
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Handling Advice Avoid freeze / thaw cycles.
Storage -20 °C/-80 °C
Storage Comment Store at -20°C (regular) and -80°C (long term).
Supplier Images
Immunohistochemistry (IHC) image for anti-Lymphotoxin beta (TNF Superfamily, Member 3) (LTB) antibody (ABIN2427427) Immunohistochemistry of Human liver cancer using LTB Polyclonal Antibody at dilution ...