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  • 产品名称:anti-tyrosineKinase,Non-Receptor,2(TNK2)antibody

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简单介绍:
anti-tyrosineKinase,Non-Receptor,2(TNK2)antibody
详情介绍:
Immunogen Synthetic peptide of human TNK2
Isotype IgG
Purification Antigen affinity purification
Alternative Name TNK2 (TNK2 Antibody Abstract)
Background This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined.
Synonyms: ACK, ACK1, ACK-1, p21cdc42Hs
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Handling Advice Avoid freeze / thaw cycles.
Storage -20 °C/-80 °C
Storage Comment Store at -20°C (regular) and -80°C (long term).
Supplier Images
Immunohistochemistry (IHC) image for anti-tyrosine Kinase, Non-Receptor, 2 (TNK2) antibody (ABIN2430961) Immunohistochemistry of Human ovarian cancer using TNK2 Polyclonal Antibody at diluti...