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  • 产品名称:anti-Cofilin1(Non-Muscle)(CFL1)antibody

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简单介绍:
anti-Cofilin1(Non-Muscle)(CFL1)antibody
详情介绍:
Immunogen Recombinant protein of human CFL1
Isotype IgG
Purification Antigen affinity purification
Alternative Name CFL1 (CFL1 Antibody Abstract)
Background The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a?pH -dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a?pH -dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.
Synonyms: CFL
Pathways Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Handling Advice Avoid freeze / thaw cycles.
Storage -20 °C/-80 °C
Storage Comment Store at -20°C (regular) and -80°C (long term).
Supplier Images
Immunohistochemistry (IHC) image for anti-Cofilin 1 (Non-Muscle) (CFL1) antibody (ABIN2429803) Immunohistochemistry of Human gastic cancer using CFL1 Polyclonal Antibody at dilutio...