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  • 产品名称：anti-NPC1antibody(Niemann-PickDisease,TypeC1)

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简单介绍：
anti-NPC1antibody(Niemann-PickDisease,TypeC1)
详情介绍：
Immunogen Synthetic peptide of human NPC1
Isotype IgG
Purification Antigen affinity purification
Alternative Name NPC1 (NPC1 Antibody Abstract)
Background This gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain. It is predicted to have a cytoplasmic C-terminus, 13 transmembrane domains, and 3 large loops in the lumen of the endosome - the last loop being at the N-terminus. This protein transports low-density lipoproteins to late endosomal/lysosomal compartments where they are hydrolized and released as free cholesterol.
Synonyms: NPC
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Handling Advice Avoid freeze / thaw cycles.
Storage -20 °C/-80 °C
Storage Comment Store at -20°C (regular) and -80°C (long term).
Supplier Images
Immunohistochemistry (IHC) image for anti-Niemann-Pick Disease, Type C1 (NPC1) antibody (ABIN2433479) Immunohistochemistry of Human liver cancer using NPC1 Polyclonal Antibody at dilution...