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  • 产品名称：anti-EID3antibody(EP300InteractingInhibitorofDifferentiation3)

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  • 产品厂商：国内供应2
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简单介绍：
anti-EID3antibody(EP300InteractingInhibitorofDifferentiation3)
详情介绍：
Immunogen Synthetic peptide of human EID3
Isotype IgG
Purification Antigen affinity purification
Alternative Name EID3 (EID3 Antibody Abstract)
Background EID3 is highly expressed in testis and shows homology to a region of EID1 implicated in binding to CBP/p300. EID3 acts as a potent inhibitor of nuclear receptor transcriptional activity by a mechanism that is independent of direct interactions with nuclear receptors, including SHP. Furthermore, EID3 directly binds to and blocks the SRC-1 interacting domain of CBP, which has been implicated to act as the interaction surface for nuclear receptor co-activators. Consistent with this idea, EID3 prevents recruitment of CBP to a natural nuclear receptor-regulated promoter.
Synonyms: NS4EB, NSE4B, NSMCE4B
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Handling Advice Avoid freeze / thaw cycles.
Storage -20 °C/-80 °C
Storage Comment Store at -20°C (regular) and -80°C (long term).
Supplier Images
Immunohistochemistry (IHC) image for anti-EP300 Interacting Inhibitor of Differentiation 3 (EID3) antibody (ABIN2432965) Immunohistochemistry of Human thyroid cancer using EID3 Polyclonal Antibody at diluti...