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  • 产品名称:anti-MTORantibody(MechanisticTargetofRapamycin(serine/threonineKinase))

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简单介绍:
anti-MTORantibody(MechanisticTargetofRapamycin(serine/threonineKinase))
详情介绍:
Immunogen Synthetic peptide of human MTOR
Isotype IgG
Purification Antigen affinity purification
Alternative Name MTOR (FRAP1 Antibody Abstract)
Background The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene.
Synonyms: FRAP, FRAP1, FRAP2, RAFT1, RAPT1
Pathways PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Handling Advice Avoid freeze / thaw cycles.
Storage -20 °C/-80 °C
Storage Comment Store at -20°C (regular) and -80°C (long term).
Supplier Images
Immunohistochemistry (IHC) image for anti-Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) antibody (ABIN2431685) Immunohistochemistry of Human brain using MTOR Polyclonal Antibody at dilution of 1:60