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  • 产品名称:anti-GAD65antibody(GlutamateDecarboxylase2(PancreaticIsletsandBrain,65kDa))

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简单介绍:
anti-GAD65antibody(GlutamateDecarboxylase2(PancreaticIsletsandBrain,65kDa))
详情介绍:
Immunogen Synthetic peptide of human GAD2
Isotype IgG
Purification Antigen affinity purification
Alternative Name GAD2 (GAD2 Antibody Abstract)
Background This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.
Synonyms: GAD65
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Handling Advice Avoid freeze / thaw cycles.
Storage -20 °C/-80 °C
Storage Comment Store at -20°C (regular) and -80°C (long term).
Supplier Images
Immunohistochemistry (IHC) image for anti-Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2) antibody (ABIN2431385) Immunohistochemistry of Human brain using GAD2 Polyclonal Antibody at dilution of 1:30